A novel mechanism for treating Idiopathic Pulmonary Fibrosis (IPF) using small molecules
World Orphan Drug Congress (Washington, DC) April-26-2018
A Proposed ADME Optimization Workflow for Covalent Inhibitors.
Drug Discovery Chemistry Symposium (San Diego, CA) April-6-2018
Efficiency in Drug Discovery: Rapid Identification of Drug-like Molecules in Drug Metabolism and Pharmacokinetics (DMPK).
IC3T Conference (Lisbon, Portugal) December-2017
Bioanalytical Strategies for Measuring Critical & Relevant Analytes of Antibody Drug Conjugates (ADC).
Americas Antibody Congress (San Diego, CA) May-24-2017
A Systematic Analysis of Physicochemical and ADME Properties of All Small Molecule Kinase Inhibitors.
Approved by US FDA from January 2001 to October 2015.
Zhihong, O’Brien, Mehran F Moghaddam. Current Medicinal Chemistry, 2017, 24, 1-26.
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression
Contributed by Bruce D. Hammock, June 11, 2020 (sent for review April 21, 2020; reviewed by Kenneth Honn and Ann C. Skulas-Ray)
HHS Public Access
Author manuscript
Mol Cancer Ther. Author manuscript; available in PMC 2019 February 01
Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor
Contributed by Bruce D. Hammock, December 5, 2018 [sent for review March 8, 2018; reviewed by Julian Gomez-Cambronero (deceased) and Laurie K. McCauley]
COX-2/sEH dual inhibitor PTUPB suppresses glioblastoma growth by targeting epidermal growth factor receptor and hyaluronan mediated motility receptor
Received: June 10, 2017 Accepted: August 26, 2017 Published: September 15, 2017
COX-2/sEH dual inhibitor PTUPB alleviates bleomycininduced pulmonary fibrosis in mice via inhibiting senescence
(Received 21 June 2019, revised 30 August 2019, accepted 23 October 2019
Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis
Contributed by Bruce D. Hammock, June 12, 2014 (sent for review April 1, 2014; reviewed by Kenneth Honn)
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